Key Takeaways: The Benefits of Water Soluble CBD, CBG and CBD Benefits:
With growing demand in functional beverages, skincare and nutraceuticals, water-soluble CBD offers versatility, faster absorption and consistent results, making it a growth opportunity for brands.
Water-soluble CBD is a form of cannabidiol that dissolves easily in water, making it ideal for beverages, skincare and other water-based products. It uses nanoemulsion technology to enhance solubility, stability, and bioavailability.
- Enhanced Bioavailability: Nano-sized particles allow for faster and more efficient absorption into the bloodstream.
- Faster Onset: Effects are felt quicker as it bypasses the liver’s first-pass metabolism.
- Lower Dosage, High Efficacy: Less CBD is needed to achieve desired effects due to improved absorption.
- Tasteless and Odorless: It integrates seamlessly into products without altering flavor or aroma.
- Formulation Flexibility: Easily blends into beverages, edibles, skincare and more.
- Increased Stability: Nanoemulsion prevents separation and ensures even CBD distribution.
- Cost-Effective: Requires less CBD raw material for effective results.
- No Additional Emulsifiers Needed: Maintains product transparency and smooth texture without extra additives.
- 10% Concentration: Ideal for standard-dose products with precise formulations.
- 20% Concentration: Suitable for high-potency CBD applications, reducing material costs.
Red Mesa adheres to cGMP and ISO-certified standards, providing third-party ISO 17025-accredited COAs for transparency and compliance. This ensures safety, purity and regulatory adherence.
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An Opportunity to Expand Into New Markets
As the market for cannabinoid-infused wellness products continues to expand, particularly in the functional beverage, skincare, cosmetics and nutraceutical industries, so too does the demand for high-quality, safe and compliant Water Soluble CBD (cannabidiol), CBG (cannabigerol) and CBN (cannabinol) raw ingredients that blend seamlessly into water-based formulations.
What Is Water Soluble CBD?
Traditional CBD isolate and CBD distillate are hydrophobic by nature, meaning they are oil-based and will not dissolve in water. While ideal for oil-based products, such as oil-based tinctures, creams and salves, this type of raw ingredient is not optimal for beverages, and serums, skincare, cosmetics or other water-based formulations.
Water-Soluble CBD, on the other hand, is a form of cannabidiol that dissolves quickly and suspends evenly in water or water-based products. Borrowed from the pharmaceutical industry to enhance the effectiveness of medications, Nanoemulsion technology greatly increases CBD solubility, stability, dosage accuracy and bioavailability, with faster uptake for quick results.
How Is Water Soluble CBD Made?
Red Mesa’s Water Soluble CBD, Water Soluble CBG and Water Soluble CBN start with 99%+ high-purity isolates manufactured within its 50,000 sq. ft. cGMP, ISO accredited, FDA-registered food facility.
Our manufacturing process begins with the highest quality US-grown hemp crude oil, which undergoes a complete inspection before entering our refinement and purification process.
- Homogenization & Solvent Recovery: The crude oil is first homogenized to ensure uniformity. This step is combined with a solvent recovery process to remove any residual solvents before refinement.
- Distillation: The oil then undergoes a two-stage distillation process. This purification method refines the oil into a high-purity distillate.
- Crystallization: The distillate is further purified through crystallization. This isolates the target cannabinoid, removing other cannabinoids, terpenes and impurities to produce a 99%+ pure isolate.
- Post-Processing Homogenization: To ensure consistent quality across production runs, multiple batches of isolate are homogenized. This process guarantees uniformity in potency, color and aroma.
- Nanoemulsification: The homogenized isolate is further processed using Red Mesa’s advanced nanoemulsion technology to reduce CBD molecules into nano-size particles and encapsulate them within a food-grade emulsifier, creating nano CBD or a CBD nanoemulsion. This critical step creates a stable, water-soluble product that consistently meets our product specifications.
Each manufacturing stage, from input hemp material to the finished water-soluble cannabinoid raw ingredient, is highly controlled with testing throughout to maintain process optimization. This results in a stable, CBD emulsion that maintains the original health and wellness benefits, while being tasteless and translucent in solution.
This same manufacturing process is applied to CBG and CBN, resulting in highly effective Water-Soluble CBG and Water-Soluble CBN raw ingredients.
Why is Water Soluble CBD, CBG and CBN Important for Product Formulations?
How Does Water Soluble CBD Enhance Customer Satisfaction?
- Enhanced Bioavailability: Bioavailability refers to the rate and extent to which a substance, such as CBD, is absorbed into the bloodstream. Water-soluble CBD, CBG or CBN is absorbed more efficiently into the bloodstream due to its nano-sized particles. These nano-sized droplets offer a larger surface area, allowing more CBD to penetrate mucus membranes directly, such as the mouth or stomach lining.
- Faster Onset of Effects: Absorption in this manner bypasses the liver’s first pass metabolism and enters the bloodstream directly, minimizing waste and allowing more CBD to be retained in the body, ultimately allowing the effects to be felt more quickly. This results in a more consistent and effective dose, as well as an optimal end-user experience, making it ideal for beverages, tinctures and functional foods like gummies where rapid relief is highly desired.
- Lower Dosage, High Efficacy with Precision Dosing: With more of the active compound reaching the bloodstream, less CBD is required to achieve the desired effects. Furthermore, the homogeneous nature of our water-soluble products enables precise and consistent dosing throughout each production batch, improving predictability and consistency, ultimately enhancing customer satisfaction.
- Tasteless and Odorless: In solution, the encapsulation of CBD, CBG, and CBN acts as a physical barrier, minimizing direct contact with the hemp flavor or aroma that some may find unpleasant, thereby allowing a cleaner flavor profile in your finished product without the need for extensive masking agents or additional flavoring. The smooth texture can make the raw ingredient less oily or gritty, resulting in a smoother mouthfeel and improved palatability.
How Does Water Soluble CBD Enhance Product Formulation and Product Development?
Water-soluble CBD generates significant opportunities for market expansion and product diversification. For product formulators and large-scale manufacturers, water-compatible CBD can expand product breadth to include beverages, water-based nutraceuticals, edibles and topical products, all capitalizing on increased bioavailability, greater absorption with accurate dosing. Formulating with Water Soluble CBD, CBG or CBN offers:
- Formulation Flexibility: Water Soluble cannabinoids dissolve quickly and blend easily into a wide variety of water-based consumer products such as RTD drinks, tinctures, gummies, gels, skincare, cosmetics and more. This versatility can expand product lines to cater to a wider customer base, from the wellness enthusiast seeking fast-acting relief to consumers interested in fast-absorbing, lightweight, effective skincare and cosmetic products.
- Increased Stability: Nano-sized cannabinoid particles ensure CBD, CBG and CBN dissolve easily and suspend evenly in water-based formulations, preventing phase separation and minimizing coalescence risk. This creates a uniform and stable dispersion, ensuring the active ingredients remain evenly distributed over time.
- No Additional Emulsifiers Required: Formulations using Water Soluble CBD, CBN or CBG remain transparent in solution, smooth in texture and shelf-stable, without requiring the addition of gums or surfactants during end-product formulation.
- Cost-Effective for Manufacturers: Because water soluble CBD isolate delivers effective results with less raw material, brands can reduce material costs while enhancing product performance.
Once mixed into a product. formulation, our Water Soluble Cannabinoids, will remian suspended in solution, which is key to increasing stability.
Product Versatility with Predictable Results Increases Customer Satisfaction
Consumers demand efficacy and consistency from their wellness products, and with CBD, CBG and CBN, it is no different. Thanks to nanoemulsion technology, water-soluble cannabinoids are absorbed quickly and efficiently by the body.
What are the applications of Water Soluble CBD in products?
In product manufacturing, dissolvability, extended stability and the ability to remain in suspension while in solution is important for water-based products such as:
- Beverages: We are seeing explosive growth in the beverage sector, with projections for a compound annual growth rate (CAGR) of 24.2% from 2024-2031. From sports drinks and energy shots to CBD-infused sparkling waters and cocktails, water-soluble CBD integrates effortlessly into ready-to-drink (RTD) formulations. The neutral flavor and transparency ensure seamless mixing without compromising taste or appearance, while our production method ensures uniform dispersion, helping to mitigate separation.
- Edibles and Supplements: Gummies, baked goods and dietary supplements benefit greatly from the precise, predictable dosing and enhanced stability offered by water-soluble CBD where oil-based ingredients may be incompatible.
- Skincare, Cosmetics and Other Topicals: Formulate greaseless, high-efficacy water-based gels, serums, cleansers, moisturizers and sprays. The enhanced bioavailability of our water-soluble cannabinoids facilitates better absorption, making them ideal for cosmetic, skincare and therapeutic topicals.
- Advanced Delivery Systems: Transdermal patches, oral sprays and dissolvable tablets leverage nano CBD to achieve faster systemic delivery, appealing to health-conscious, results-driven buyers.
What are the Strategic Advantages of Using Water Soluble Cannabinoids?
In large-scale manufacturing, the physical properties and performance of an ingredient are critical and directly impact production efficiency, scalability and material costs. Our Water Soluble CBD, Water Soluble CBG and Water Soluble CBN are offered in both 10% and 20% concentrations to provide flexibility in aligning with specific formulation and budgetary requirements.
- 10% Concentration: An ideal solution for standard-dose products. It offers precision formulations where lower cannabinoid content per unit is required, ensuring consistency across large batches.
- 20% Concentration: Engineered for high-potency applications. This higher concentration can increase end-product potency or reduce the input material, helping trim material costs.
How to Build Trust
Clear labeling and ISO-17025 third-party accredited final certificate of analysis (COAs).
Water-soluble CBD manufactured under cGMP and ISO-certified guidance ensures regulatory compliance and transparency. With full-panel ISO 17025 accredited third-party COA documentation confirming potency, brands can instill consumer trust and confidence in market products knowing they meet, if not exceed, strict industry standards.
Strategically, It’s Time to Take the Next Step
Integrating water-soluble CBD into your product portfolio should no longer just be an option, but rather imperative to remaining competitive. Partnering with a reliable, well-established water-soluble manufacturer is essential to your brand integrity and to meet your quality and scalability needs. As a proven global hemp-derived manufacturer of cannabinoid raw materials, Red Mesa is positioned to help grow your brand.
More about Red Mesa Science & Refining
How Does Red Mesa Ensure the Quality of its Water Soluble CBD?
Red Mesa Science & Refining stands out as an ideal partner for product formulators seeking bulk water-soluble CBD, CBG, CBN and other cannabinoid raw materials. Red Mesa’s commitment to Operational Excellence, quality, and innovation is evident in its cGMP conformance, ISO 9001:2015 certification, 21 CFR Parts 111 & 117 certifications, and FDA registration, all exceeding industry standards. This ensures that Red Mesa products consistently meet, if not exceed, the highest quality benchmarks, offering formulators peace of mind regarding safety, purity and regulatory compliance.
Why is Red Mesa Chosen Worldwide as the Supplier of Choice?
Red Mesa’s significant investment in human capital and advanced manufacturing capabilities, along with advanced processes, is rare in the industry. Additionally, Red Mesa’s in-house labs for process optimization and traceable production processes ensure reliability and transparency for added confidence. This, combined with Red Mesa’s customer-centric approach, including collaborative support and timely deliveries, fosters long-term partnerships and drives Red Mesa’s success.
Red Mesa’s extensive product range, from isolates to distillates to water-solubles, caters to diverse formulation needs, with flexible order quantities that accommodate both large-scale industrial applications and smaller R&D projects. For formulators prioritizing quality, innovation and dependable supply chains, Red Mesa Science & Refining is a clear leader in the hemp industry.


