Red Mesa’s CBN Isolate-Botanical is a non-synthetic CBN raw material refined and purified without chemical catalyst conversions. Beginning with fully traceable high-quality hemp plant material, our CBN Isolate – Botanical is refined naturally, satisfying consumer-led demands and providing acceptable alternatives to states prohibiting synthetic/alternative cannabinoids.

CBN Isolate – Botanical’s exceptional purity, with a guaranteed 95% CBN concentration, ensures that the final product is potent and delivers the intended targeted therapeutic benefits naturally. As an ingredient, CBN Isolate – Botanical can be accurately measured with its concentration adjusted to meet product specifications, which is essential for achieving product consistency. This Cannabinol Isolate, also known as CBN Isolate, can be incorporated into a wide range of product formulations, catering to diverse consumer preferences.

Common CBN Isolate powder applications include:

  • Tinctures and Oils
  • Capsules and Soft gels
  • Edibles – Gummies, Chocolates and Other Confections
  • Topicals – Creams, Lotions, Balms, Salves etc.


Need a larger quantity? Please contact us for custom wholesale quotes to buy larger bulk quantities or request current batch CoAs. You can also reach us via phone or email: 435.677.6363

CBN Isolate - Botanical is a non-synthetic botanically refined cannabinol raw ingredient that is manufactured void of any chemical catalyst conversions. CBL Isolate - Botanical is guaranteed THC-Free and 95% CBN, making it ideal to satisfy consumer-led demands and provide an acceptable alternative to states prohibiting synthetic/alternative cannabinoids.
CBN Isolate - Botanical is a non-synthetic botanically refined cannabinol raw ingredient that is manufactured void of any chemical catalyst conversions. CBL Isolate - Botanical is guaranteed THC-Free and 95% CBN, making it ideal to satisfy consumer-led demands and provide an acceptable alternative to states prohibiting synthetic/alternative cannabinoids.
CBN Isolate Non-Synthetic Botanically Refined Hemp CBN
CBN Isolate - Botanical non-synthetic THC-Free 95 percent CBN
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Red Mesa Science & Refining's Quality Badge represents the use of an ISO 17025 accredited third party lab COAs to validate Red Mesa's CBD Isolate, CBD Distillate, CBG Isolate and CBG Distillate high quality and trustworthiness.

Delivering What We Promise

Full panel ISO 17025 Accredited Third-Party Lab COAs for added confidence.

  • ≥ 95% Pure CBN Guaranteed
  • ≤ 0.01% THC
  • Made in the USA – American Grown and Processed Industrial Hemp
  • Fragrance – Odor Free
  • Taste – Flavorless
  • Appearance – Bright White Crystalline Powder
The Made in the USA badge communicates that all of Red Mesa Science and Refining CBD Isolates and Distillates, CBG Iso;atesa nd Distillates, CBN Isolates and Distillates are made in the USA
THe FDA Registered Food Facility badge communicates that Red Mesa Science & Refining is an FDA Registered Food Facility
cGMP Badge demonstrates that Red Mesa Science & Refining is following current good manufacturing practices to provide high quality products with complete transparency
ISO 17025 badge demonstrates that Red Mesa Science and Refining uses an ISO 17025 accredited third party lab for COAs to communicate trust in the quality and potency of our cannabinoids.
ISO 9001:2015 certification badge demonstrates Red Mesa Science & Refining operates to the highest quality standards and is continuously improving upon procedures and methods for increased customer satisfaction.
Badge for GMP Compliant Human Food to demonstrate Red mesa Science & Refining adheres to 21 CFR 117 regulations
The GMP Compliant 21 CFR 111 badge represents Compliant Dietary Supplement processes and demonstrates Red Mesa Science & Refining adheres to 21 CFR 111 regulations
100% guarantee of satisfactions badge communicates our guarantee to customers who purchase our CBD, CBG, CBN cannabinoid raw ingredients.
The Non-GMO badge demonstrate that Red Mesa Science & Refining cbd, cbg, cbn cannabinoid raw ingredients are non-gmo
Vegan badge demostrates that Red Mesa Science & Refining's cbd, cbg, cbn cannabinoid raw ingredients are vegan.

It’s About Trust

Our ISO 17025 accredited third-party lab tests every batch for cannabinoid profile, residual solvents, pesticides, heavy metals, microbial counts and mycotoxins per R68-37 assuring our products meet our quality standards as well as current federal and state regulations (read more).

The Promises We Speak Of Are The Results We Deliver.

The downloadable CBN Isolate – Botanical Product Specifications Sheet provides guaranteed minimum cannabinoid concentration levels and product characteristics you can count on with each order placed.

For your convenience, we have provided a CBN Isolate – Botanical Sell Sheet available for download to keep for yourself or share with others. 

Thoughtful Packaging Secures Contents and Promotes Longevity

Our CBN Isolate – Botanical is packaged in either food-grade bags or food-grade HDPE containers. Our stand-up EU & US FDA compliant polyethylene bags hold up to 10 kgs with tear notch and re-closable zipper for easy dispensing and disposal with less environmental waste. HDPE container to preserve freshness and shelf life by reducing light exposure and to help maintain temperature control. The screw-top lid keeps out excess oxygen and other potential contaminants as well as being tamper resistant. Our packaging comes with a label listing the Lot ID number, manufactured date and a QR code to access ISO 17025 accredited third-party CoA reports quickly.

CBN Isolate - Botanical | Step Change Refinement Process

CBN Isolate - Botanical is botanically refined using an advanced chromatographic method to separate cannabinol from other materials without chemical catalyst conversions. The resulting non-synthetic CBN is guaranteed to be THC-Free and contains 95% + CBN. CBN Isolate - Botanical is ideal for demand-driven formulations that seek a natural CBN raw ingredient that is also an acceptable substitute for states that have banned synthetic/alternative cannabinoids.


Producing our botanically derived CBN Isolate – Botanical is a complex and time-consuming process using advanced chromatographic separation methodologies, resulting in lower outputs than other less demanding processes. But this is precisely why our CBN Isolate – Botanical stands out as a premium Cannabinol Isolate. Its rarity and unique production method provide ample opportunities for product innovation and market differentiation.


Processed in our FDA Food Registered, cGMP adherent, ISO 9001:2015 certified facility, our CBN Isolate – Botanical is manufactured adhering to both dietary supplements (21 CFR Part 111) as well as food and beverage (21 CFR Part 117) regulations to ensure quality, potency and purity. Additionally, our in-house lab utilzing advanced equipment, including HPLC units, allows for routine analytical testing throughout manufacturing to evaluate consistency, production controls and optimization of processes. 

Frequently Asked Questions about CBD Full Spectrum Compliant Distillate

The Full Spectrum Compliant Distillate refinement process retains the available profile of cannabinoids, including THC, CBD and other cannabinoids. This unique combination contributes to the Entourage Effect, a theory where different cannabinoids work synergistically to enhance the overall efficacy and benefits.

Full Spectrum Compliant Distillate strictly adheres to all applicable regulations and industry standards. Our manufacturing processes ensure compliance with legal limits of THC, ensuring that the product is fully compliant with the Federally regulated ≤ 0.3% THC allowance. After refinement, every batch undergoes comprehensive ISO 17025 accredited third-party testing to ensure its purity and potency, verify compliance with THC limits, and ensure that our distillate complies with the removal of contaminants. COAs are available upon request, to provide complete transparency and peace of mind to formulators and their customers.

Full Spectrum Distillate – Compliant has a similar cannabinoid profile to Full Spectrum Distillate with the exception that it is lower in THC and guaranteed to be equal to or less than 0.3%, meeting the federally mandated limit of THC as opposed to Full Spectrum Distillate which is higher in THC. 

Compliant Full Spectrum Distillate and Broad Spectrum Distillate both contain a wide range of cannabinoids extracted from the hemp plant, and both are believed to contribute to the entourage effect. The most significant difference is that Broad Spectrum Distillate is refined further to remove THC to non-detectable levels, while Full Spectrum Distillate – Compliant is refined to retain a federally compliant level of THC for those that seek to preserve all available cannabinoids for a more holistic approach.

Selection between Full Spectrum Compliant Distillate and Broad Spectrum Distillate may come down to the desire to include a trace amount of THC or to exclude it. Full Spectrum Distillate – Complaint with its trace amounts of THC may potentially contribute to better symptom relief due to the entourage effect and the unique characteristics of THC. Whereas Broad Spectrum Distillate is a better choice when the desire is to exclude THC altogether from products, perhaps due to jurisdictional regulations or belief inclusion may discourage those who are sensitive to THC from purchasing product.

Red Mesa sells to product formulators, co-packers, distributors and other B2B customers. Wholesale Compliant Full Spectrum Distillate can be purchased directly from our website or quoted at bulk Full Spectrum Compliant Distillate wholesale pricing for larger quantities. 

If you have any additional questions or require further assistance, please contact our sales support team. We’re here to help you make informed decisions to provide your customers with the highest quality CBD, CBG, CBN and other minor cannabinoid raw ingredients to grow brand loyalty and help protect your brand reputation.

We offer Full Spectrum Distillate – Compliant in various quantities, from small quantities for R&D and small-scale formulation needs starting at 25 grams to larger volumes for commercial manufacturing in the hundreds of kgs. Our flexible ordering options allow you to choose the most appropriate volume for your requirements.

Yes, the third-party lab we send our batch-specific Full Spectrum Distillate – Compliant samples to has been inspected and has demonstrated operational competency with the ability to generate valid testing results to earn the ISO 17025 accreditation. This level of accreditation is vital for Red Mesa Science & Refining to extend confidence in the quality of our products to our customers. (read more)

Red Mesa Science & Refining has received and has maintained a comprehensive end-to-end ISO 9001:2015 certification. (read more)

Red Mesa Science & Refining is registered as a food facility with the FDA and subject to random inspections. (read more)

Yes, as a hemp processor in the state of Utah, we are required to adhere to cGMP requirements for dietary supplements and human food. (read more)

As a science-based, innovative company we collaborate with our customers providing valuable insight into helping choose the ideal cannabinoid characteristics, purity levels, blends etc. for their end product formulations. Please contact us to discuss your specific formulating needs.

Why Choose Red Mesa Science & Refining for Your Bulk Cannabinoid Raw Ingredients?

Prioritizing Quality Assurance – Quality is Central to Manufacturing CBN Isolate – Botanical

Quality Assurance is at the heart of our production process. We prioritize quality by operating under stringent guidelines to ensure our customers receive products that abide by regulations and meet or exceed industry standards.

Quality and  Regulatory Compliance at the Forefront

  • Strict Quality Management System – Under the guidance of ISO 9001:2015 certification and cGMP, our production processes are focused intently on optimal quality and safety.
  • Higher Standards – Red Mesa is uniquely held accountable to adhere to both 21 CFR Part 111 (dietary supplements) and 21 CFR Part 117 (food and beverage) standards, furthering our commitment to ensuring our CBD Isolate is of the highest quality.
  • Internal Testing Protocols – We thoroughly examine, test and analyze the CBD Isolate material through to completion. Our team of onsite scientists and chemists perform routine analytical tests throughout production to uphold our promise to guarantee the consistent delivery of products to guaranteed specifications. 
  • ISO 17025 Accredited Trustworthy and Reliable COAs – Upon completion of manufacturing, final batch-specific testing is administered by an independent ISO 17025 accredited third-party laboratory. The resulting COAs provide added confidence in verifying cannabinoid potency and compliance regarding pesticides, residual solvents, heavy metals, mycotoxins and any other undesirable impurities.
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