CBL ISOLATE – BOTANICAL
CBL, or Cannabicyclol, is an extraordinarily rare cannabinoid found within the hemp plant after CBC (cannabichromene) has oxidized into CBL. Due to its scarcity and the significant rise in demand, Red Mesa developed a proprietary method to refine and purify bulk CBL Isolate – Botanical quantities without using conventional chemical conversion methodologies. The result is a natural, non-synthetic CBL raw material derived from high-quality, fully traceable, federally compliant hemp aimed at strengthening your competitive edge.
Buy CBL Isolate wholesale at low MOQs or in Kilogram quantities.
From: $798.00
Need a larger quantity? Contact us for a personalized request for quotation (RFQ) on orders exceeding 20kg.





Delivering What We Promise
Full panel ISO 17025 Accredited Third-Party Lab COAs for added confidence.
- ≥ 90% Pure CBL Guaranteed
- ≤ 0.01% THC
- Made in the USA – American Grown and Processed Industrial Hemp
- Appearance – Off-White Crystalline Powder
- Fragrance – Odor Free
- Taste – Flavorless
- Other – Kosher, Halal, Vegan and Non-GMO
ISO 17025-accredited third-party lab COAs ensure the reliability, accuracy, compliance and credibility of our cannabinoid raw materials, while also demonstrating our commitment to safety, quality and consumer trust.
Batch-specific COAs are conveniently accessible via the QR code on the package label or available upon request. To view a COA representative of CBL Isolate – Botanical’s full-panel test results, click the “Download COA” button below.
- Compliance
- Quality Assurance
- COAs
- MOQs, Wholesale Pricing & Lead Times
We are the Benchmark
COMPLIANCE – Red Mesa’s high-purity ≥ 90% CBL Isolate – Botanical is manufactured using highly sophisticated equipment and scientific methods, while strictly adhering to:
- cGMP
- ISO 9001:2015 certification
- FDA-registered food facility
- 2018 Farm Bill Compliant (ND Δ9 THC)
This commitment to Operational Excellence ensures regulatory compliance beyond what’s required, full traceability (seed to sale), consistency and repeatable performance across batches, all of which are critical to brand integrity and highly regulated markets.
Quality From Start to Finish
PRIORITIZING QA – From the initial comprehensive 6-point qualifying inspection of input material through to our final raw material packaging, strict adherence to processes, protocols and reporting with extensive QA oversight is absolutely essential to deliver what we promise.
ANALYTICAL TESTING – Throughout manufacturing, Red Mesa routinely performs analytical testing using our in-house HPLC (High-Performance Liquid Chromatography) in addition to other lab equipment to evaluate consistency, production controls and process optimization.
It’s About Trust
THIRD-PARTY TESTING – Each bulk CBL Isolate – Botanical batch undergoes testing by an independent ISO 17025-Accredited Third-party Lab. ISO 17025 accreditation ensures that labs are internationally recognized as technically competent and provide reliable, accurate test results, instilling the utmost confidence and trustworthiness. Our batch-specific ISO 17025-Accredited Third-party Lab Certificates of Analysis (COAs) test and verify:
- Precise CBL Purity and Potency
- Compliant, Non-detectable THC levels
- Absence of Minor Cannabinoids
- Terpene removal
- Federally compliant removal of residual solvents, heavy metals, pesticides and mycotoxins.
Our COAs confirm that our products are 2018 Farm Bill–compliant, meet our rigorous internal quality standards, and comply with current federal & state regulations (read more).
Minimum Order Quantities (MOQs), Best CBL Isolate – Botanical Wholesale Prices and Lead Times
MOQs – Botanical CBL Isolate is available in scalable packaging configurations, with MOQs starting at 25g for sampling and R&D.
BULK WHOLESALE PRICES – Wholesale pricing is available here online, providing access to our most competitive pricing 24/7. For commercial orders exceeding 20kg, we offer volume-based pricing tiers tailored to your operational scale. Schedule a call with our team for a custom quote and logistics support.
LEAD TIMES – We do our best to ship the same day, depending on available stock, the time of day the order is received, and the order’s complexity. For bulk CBL Isolate – Botanical purchases, our Sales Team can provide you with an estimated lead time based on your order requirements.
CBL ISOLATE - BOTANICAL | Refined Without Acids or Catalysts Conversions
LEADING THE INDUSTRY IN CBL BOTANICAL REFINEMENT AT SCALE
The production of CBL Isolate – Botanical requires complex refinement and purification processes utilizing advanced chromatographic separation methodologies without chemical conversions. The sophisticated manufacturing process retains the highest concentration of CBL and consistently delivers CBL purity and potency uniformity across batches. Onsite analytical testing throughout manufacturing ensures our CBL Isolate – Botanical meets, and often exceeds, our guaranteed product specifications
ASSURING CBL ISOLATE - BOTANICAL IS OF THE HIGHEST QUALITY
Processed in our FDA Food Registered, cGMP adherent, ISO 9001:2015 certified facility, our CBL Isolate – Botanical is manufactured adhering to both the FDAs dietary supplement (21 CFR Part 111) and to food and beverage (21 CFR Part 117) regulations to ensure quality, potency and purity. Additionally, our in-house lab utilzing advanced equipment, including HPLC units, allows for routine analytical testing throughout manufacturing to evaluate consistency, production controls and optimization of processes.
How to Use CBL Isolate
Given its rarity and unique properties, CBL Isolate – Botanical is an ideal ingredient to introduce innovative products to further differentiate your brand within a crowded market space. The natural purity of CBL Isolate – Botanical appeals to formators seeking to create products that resonate with customers seeking botanically refined ingredients. Its nearly tasteless and odorless properties allow for seamless integration into various formulations with little to no influence on taste or aroma profiles.
What Are Some Common CBL Isolate powder applications?
- Tinctures and Oils
- Capsules and Soft gels
- Edibles – Gummies, Chocolates and Other Confections
- Topicals – Creams, Lotions, Balms, Salves, skincare etc.
Our botanically derived CBL Isolate – botanical is THC-Free and guaranteed to be at least 90% pure CBL to support greater accuracy in dosing and predictability in end-product potency. This consistency, backed by ISO 17025-accredited third-party COAs, provides added confidence to end users targeting unique health and wellness benefits.

