CBN Isolate
What is CBN Isolate?
CBN Isolate, a fine CBN crystalline powder, is the purest form of cannabinol with a guaranteed ≥ 98% CBN purity. With precise dosing and little to no influence on flavor, aroma or physical properties, CBN Isolate is gaining significant traction in product development for its health and wellness benefits (Explore CBN studies).
Bulk CBN Isolate at Wholesale Prices
DIRECT FROM THE MANUFACTURER – Wholesale CBN Isolate can be purchased with MOQs starting at 25g up to multiple kgs for a faster, easier and more cost-effective way to source the highest-quality CBN raw ingredients. For quantities above 20 kg, our team will provide personalized quotes and can also assist with international documentation and shipping logistics.
KG Volume-based Tier Bulk Pricing
| Order QTY | Price/Kilo |
|---|---|
|
1kg |
$1250 |
|
5kg |
$1187 |
|
10 – 20 kg |
$1125 |
From: $125.00
Need a larger quantity? Contact us for a personalized request for quotation (RFQ) on orders exceeding 20kg.
Delivering What We Promise
Full panel ISO 17025 Accredited Third-Party Lab COAs for added confidence.
CBN Isolate Product Specifications
- ≥ 98% Pure CBN Guaranteed
- ≤ 0.3% THC (Non-detect, THC-Free)
- Made in the USA – American Grown and Processed Industrial Hemp
- Appearance – Off-White Crystalline Powder
- Fragrance – Little to none
- Taste – Little to none
- Solubility: Oil-Soluble
- MOQ – 25g
- Other – Kosher, Halal, Vegan and Non-GMO
ISO 17025-accredited third-party lab COAs ensure the reliability, accuracy, compliance and credibility of our cannabinoid raw materials, while also demonstrating our commitment to safety, quality and consumer trust.
We are the Benchmark
COMPLIANCE – Red Mesa’s high-purity ≥ 98% CBN Isolate Powder is manufactured using highly sophisticated scientific methods and processes strictly adhering to:
- cGMP
- ISO 9001:2015 certification
- FDA-registered food facility
- 21 CFR Parts 111 (Dietary Supplements)
- 21 CFR Parts 117 (Food and Beverage)
- 2018 Farm Bill Compliant (ND Δ9 THC)
This commitment to Operational Excellence ensures regulatory compliance beyond what’s required, full traceability (seed to sale), consistency and repeatable performance across batches, all of which are critical to brand integrity and highly regulated markets.
Quality From Start to Finish
PRIORITIZING QA – From the initial comprehensive 6-point qualifying inspection of input material through to our final raw material packaging, strict adherence to processes, protocols and reporting with extensive QA oversight is absolutely essential to deliver what we promise.
ANALYTICAL TESTING – Throughout manufacturing, Red Mesa routinely performs analytical testing using our in-house HPLC (High-Performance Liquid Chromatography) in addition to other lab equipment to evaluate consistency, production controls and process optimization.
It’s About Trust
THIRD-PARTY TESTING – Each bulk CBN Isolate batch undergoes testing by an independent ISO 17025-Accredited Third-party Lab. ISO 17025 accreditation ensures that labs are internationally recognized as technically competent and provide reliable, accurate test results, instilling the utmost confidence and trustworthiness. Our batch-specific ISO 17025-Accredited Third-party Lab Certificates of Analysis (COAs) test and verify:
- Precise CBN Purity and Potency
- Compliant, Non-detectable THC levels
- Absence of Minor Cannabinoids
- Terpene removal
- Federally compliant removal of residual solvents, heavy metals, pesticides, mycotoxins and microbial contamination.
ISO 17025 third-party lab COAs per lot number are conveniently accessible via the QR code on the package label or available upon request. Our COAs confirm that our products are 2018 Farm Bill compliant, meet our rigorous internal quality standards and comply with current federal & state regulations (read more).
Wholesale CBN Isolate Minimum Order Quantities (MOQs) and Lead Time
MOQs – CBN Isolate is available in scalable packaging configurations, with MOQs starting at 25g for sampling and R&D. For larger commercial applications (above 20kgs), book a call to discuss wholesale CBN Isolate bulk-tier pricing and logistics.
LEAD TIMES – We do our best to ship the same day, depending on available stock, the time of day the order is received, and the complexity of the order. For bulk CBN Isolate , our sales team can provide you with an estimated lead time based on your order requirements
RED MESA'S REFINEMENT PROCESS - SCIENCE AND INNOVATION AT ITS BEST
Red Mesa Manufacturers High Purity CBN Raw Ingredients for Finished Products
CBN is considered a rare minor cannabinoid with only trace amounts recovered when CBN is extracted directly from hemp. Understanding the promising benefits of CBN, our scientists and chemists have developed a sulfur-free method to convert other hemp-derived carboxylic acid forms of cannabinoids into CBN at commercial scale. Once produced, the bulk CBN raw material is transferred to a custom-built crystallization system to further refine and purify, producing a fine CBN powder that is nearly 100% pure CBN.
While most manufacturers stop here, Red Mesa further enhances the quality of our bulk CBN isolate using industrial pharmaceutical-grade homogenization equipment to ensure consistency across multiple batches of up to 500kg. Final sifting helps eliminate clumping, consistently producing light, fluffy, ultra-pure, THC-Free CBN Isolate powder that can be scaled up to meet growing demand.
Developed through multiple gates of operation, our manufacturing process for refining and purifying bulk CBN Isolate is complex and requires immense technical expertise, with specialized equipment used at nearly every stage. Learn more about the equipment used to refine and purify CBN Isolate.
What is CBN Isolate Used For?
Our wholesale CBN Isolate Powder is designed for global formulators, large-brand manufacturers and contract manufacturers who require consistent quality and compliance with a clear, documented chain of custody.
As a versatile, highly sought-after raw ingredient, CBN is gaining traction in industry verticals such as nutraceuticals, wellness products, skincare and cosmetics for its health and wellness benefits with minimal impact, if any, on flavor, aroma or visual profiles. CBN is commonly added to wellness products intended for evening and nighttime use for sleep cycle support and recovery.
Applications:
- Tinctures and Oils
- Gummies and Other Edibles
- Capsules and Softgels
- Food and Beverages
- Skincare, Cosmetics and Other Topicals
- Pet Wellness Products
Read our article for an expanded discussion regarding CBN’s best use cases here.
Frequently Asked Questions about CBN Isolate Powder
Why is CBN Considered Rare?
In nature, CBN is formed when THC oxidizes and decomposes, typically through exposure to air or heat. However, because Industrial Hemp must be ≤ 0.3% THC by dry weight, the opportunity to produce hemp-derived CBN through oxidation is minimal, making CBN a rare minor cannabinoid due to its scarcity in nature. Fortunately, scientists and chemists have developed sophisticated methods to produce CBN Isolate from other cannabinoids at commercial scale to meet rising demand.
How Pure is CBN Isolate?
High-quality CBN Isolate typically tests at 97% – 99% CBN. It is produced by removing all other cannabinoids, terpenes, flavonoids, waxes, and plant material from hemp extract, resulting in a nealry 100% pure CBN white, odorless crystalline powder.
Always insist on COAs – Testing by third-party labs will provide Certificates of Analysis (COAs) to confirm potency and contaminant analysis.
Does CBN Work?
CBN interacts with the body’s endocannabinoid system by binding primarily to the CB2 receptor with minor interactions with the CB1 receptors. Within the endocannabinoid system, the CB2 receptor is associated with the immune system showing that it may modulate immune cell functions.
Promising preliminary research has indicated that CBN may have potential therapeutic benefits in promoting sleep with additional anti-inflammatory and immunosuppressive properties with continued interest in CBNs potential to trigger apoptosis (cell death) to inhibit tumor cell growth in some cancers.
Is CBN Isolate Psychoactive?
Is CBN Isolate THC-Free
Yes, CBN Isolate is inherently THC-Free when properly manufactured and verified by testing. In nature, CBN Isolate is not a form of THC, although CBN can be converted from the oxidation of THC. Reputable manufacturers will provide third-party Certificates of Analysis (COAs) confirming non-detect delta 9 THC, typically below 0.01%
Is CBN Legal in the United States and Abroad?
CBN (Cannabinol) is one of many cannabinoids in the cannabis plant. The legality of CBN depends on the specific jurisdiction and the source from which it is derived. In many countries, including the United States, the legal status of cannabinoids is primarily determined by whether they are derived from marijuana or hemp.
CBN derived from hemp is generally legal in the United States as long as it complies with the 2018 Farm Bill and contains levels below the legal limit of 0.3% THC by dry weight. Globally, in some jurisdictions, CBN Isolate can not be imported unless it is ≤ 0.001% or ≤ 10ppm D9-THC (ND), such as is the case for Japan.
As with any cannabis-derived product, checking the legality of CBN in your jurisdiction is essential, as cannabis laws can vary from place to place.
How Do I Buy CBN Isolate Wholesale and What Are Your Minimum order quantities (MOQs)?
Red Mesa sells to product formulators, co-packers, distributors and other B2B customers. We offer CBN Isolate in various quantities, from MOQs for R&D and small-scale formulation needs starting at 25 grams to larger volumes for commercial manufacturing in the hundreds to thousands of kgs. Our flexible ordering options allow you to choose the most appropriate volume for your requirements, with wholesale CBN Isolate being purchased directly from our website or quoted at bulk CBN Isolate wholesale pricing for quantities over 20kgs.
If you have any additional questions or require further assistance, please contact our sales support team. We’re here to help you make informed decisions to provide your customers with the highest-quality CBD, CBG, CBN and other minor cannabinoid raw ingredients, to grow brand loyalty and help protect your brand reputation.
How should CBN Isolate be Stored?
CBN Isolate Powder should be stored in airtight, food-grade containers away from direct light, below 77º F (25º C) and away from humidity.
Does CBN Isolate Dissolve in Water?
CBN Isolate is not water-soluble in its natural form. It is fat-soluble and dissolves well in oils. Choose Water Soluble CBN Isolate that has been nanoemulsified if. your product formulation is water-based formulations, like beverages, serums, gummies etc.,
What's the Difference Between CBD and CBN?
Both CBN (Cannabinol) and CBD (cannabidiol) are cannabinoids found in the cannabis plant, but with some key differences:
Chemical Structure – CBN and CBD have different chemical structures. CBN is a minor cannabinoid naturally derived from THC through oxidation and decomposition unless converted in a laboratory using other cannabinoids as a base. CBD, in comparison, is a major cannabinoid, being one of two predominant cannabinoids, occurring naturally present within the plant without being a degradation product.
Psychoactive Effects – Both CBN and CBD are non-intoxicating cannabinoids. CBN is generally considered to have mild sedative properties, which may contribute to its potential calming and relaxing effects. It is often associated with promoting sleep and has been reported to have a more sedative effect than CBD. On the other hand, CBD is considered non-intoxicating and is often associated with potential anti-anxiety and anti-inflammatory effects.
Potential Benefits – Although having some similar properties due to their structural similarities, CBN and CBD have different effects on the endocannabinoid system and interact with different cannabinoid receptors.
Of the two, CBD has been more extensively studied and is associated with potential therapeutic benefits, including pain relief, reducing anxiety, aiding in sleep and potentially addressing certain seizure disorders. Having been less studied, CBN is believed to have potential benefits for sleep promotion, anti-inflammatory, analgesic (pain-relieving), antibacterial effects and appetite stimulation. While CBN and CBD have shown promise in various areas, research is ongoing to understand their effects fully.
Availability and Regulation– Regulations regarding CBN and CBD can vary between countries and regions, with accessibility being readily available or limited according to jurisdictions. CBD has gained wider acceptance and is more available in many parts of the world. It is used in various products such as oils, capsules, topicals, and edibles. On the other hand, CBN is less common and may be found in specific products targeting sleep or relaxation.
CBN vs CBG
CBN (Cannabinol) and CBG (Cannabigerol) are two different compounds found in the cannabis sativa plant, alongside the more well-known cannabinoids THC and CBD (cannabidiol).
CBN is a cannabinoid that is formed naturally from the degradation of THC. When THC is exposed to oxygen and light, it degrades gradually to form CBN. Due to the rare occurrence of CBN within the hemp plant, scientists and chemists have developed methods to convert base cannabinoids such as CBDa and CBGa into CBN. CBN is often associated with promoting relaxation and aiding sleep. Some research suggests that CBN may have potential therapeutic effects, such as pain relief and anti-inflammatory properties, but further studies are needed to understand its potential benefits fully.
CBG is considered a minor cannabinoid because of its low concentration in most cannabis strains. However, genetics has produced a CBG-rich hemp strain, enabling high-concentration CBG extraction. CBG is known as the “mother of all cannabinoids” because it serves as the precursor molecule from which other cannabinoids, including THC and CBD. CBG has gained attention for its potential therapeutic properties, including anti-inflammatory, analgesic (pain-relieving), and antibacterial effects. Some research also suggests that CBG may have neuroprotective properties, potentially beneficial for certain neurological conditions.
What is the Difference Between CBN Isolate and Full Spectrum?
- CBN Isolate: Contains only Cannabinol, and zero THC or other cannabinoids.
- Full Spectrum: Contains CBN, CBD and other minor cannabinoids and trace THC (2-5% THC).
CBN Isolate is the ideal choice for the avoidance of THC, to support regulatory clarity and export compliance.
What Certifications Should CBN Isolate Suppliers provide?
Important documentation or certification of importance includes:
- Certificate of analysis (COA)
- CBN potency
- heavy metals, pesticides and residual solvent testing results
- Hemp Source and farm records
- THC compliance
- GMP and ISO certifications
Is your CBN Isolate Third-party Tested by an ISO 17025 Accredited Third-party Lab?
Is Red Mesa Science & Refining ISO Certified?
Is Red Mesa Science & Refining FDA Registered?
Is Red Mesa Science & Refining complying with cGMP requirements for Dietary supplements and human food?
Do you Provide Formulation Support?
Why Choose Red Mesa Science & Refining for Your Bulk Cannabinoid Raw Ingredients?
Prioritizing Quality Assurance – Quality is Central to Manufacturing CBN Isolate
Quality Assurance is at the heart of our production process. We prioritize quality by operating under stringent guidelines to ensure our customers receive products that abide by regulations and meet or exceed industry standards.
Quality and Regulatory Compliance at the Forefront
- Strict Quality Management System – Under the guidance of and, our production processes are focused on optimal quality and safety.
- Higher Standards – Red Mesa is uniquely held accountable to adhere to both 21 CFR Part 111 (dietary supplements) and 21 CFR Part 117 (food and beverage) standards, furthering our commitment to ensuring our CBN Isolate is of the highest quality.
- Internal Testing Protocols—We thoroughly examine, test and analyze the CBN Isolate material from start to finish. Our team of on-site scientists and chemists performs routine analytical tests throughout production to uphold our promise to guarantee the consistent delivery of products to guaranteed specifications.
- ISO 17025 Accredited Trustworthy and Reliable COAs – Upon completion of manufacturing, final batch-specific testing is administered by an independent ISO 17025 accredited third-party laboratory. The resulting COAs provide added confidence in verifying cannabinoid potency and compliance regarding pesticides, residual solvents, heavy metals, mycotoxins and any other undesirable impurities.
