CBL ISOLATE – BOTANICAL
CBL, or Cannabicyclol, is an extraordinarily rare cannabinoid found within the hemp plant after CBC (cannabichromene) has oxidized into CBL. Due to its scarcity and the significant rise in demand, Red Mesa developed a proprietary method to refine and purify bulk CBL Isolate – Botanical quantities without using conventional chemical conversion methodologies. The result is a natural, non-synthetic CBL raw material derived from high-quality, fully traceable, federally compliant hemp aimed at strengthening your competitive edge.
Given its rarity and unique properties, CBL Isolate – Botanical is an ideal ingredient to introduce innovative products to further differentiate your brand within a crowded market space. The natural purity of CBL Isolate – Botanical appeals to formators seeking to create products that resonate with customers seeking botanically refined ingredients. Its nearly tasteless and odorless properties allow for seamless integration into various formulations with little to no influence on taste or aroma profiles.
Common CBL Isolate powder applications include:
- Tinctures and Oils
- Capsules and Soft gels
- Edibles – Gummies, Chocolates and Other Confections
- Topicals – Creams, Lotions, Balms, Salves, skincare etc.
Our botanically derived CBL Isolate – botanical is THC-Free and guaranteed to be at least 90% pure CBL to support greater accuracy in dosing and predictability in end-product potency. This consistency backed with ISO 17025 accredited third-party COAs provides added confidence to end users targeting unique health and wellness benefits.
Buy CBL Isolate wholesale at low MOQs or in Kilogram quantities.
From: $309.00
Need a larger quantity? Please contact us for custom wholesale quotes to buy larger bulk quantities or request current batch CoAs.





Delivering What We Promise
Full panel ISO 17025 Accredited Third-Party Lab COAs for added confidence.
- ≥ 90% Pure CBL Guaranteed
- ≤ 0.01% THC
- Made in the USA – American Grown and Processed Industrial Hemp
- Fragrance – Odor Free
- Taste – Flavorless
- Appearance – White Crystalline Powder
- Other – Kosher, Halal, Vegan and Non-GMO









- CoAs
- Specifications Download
- Sell Sheet Download
- Packaging
It’s About Trust
Our ISO 17025 accredited third-party lab tests every batch for cannabinoid profile, residual solvents, pesticides, heavy metals, microbial counts and mycotoxins per R68-37 assuring our products meet our quality standards as well as current federal and state regulations (read more).
The Promises We Speak Of Are The Results We Deliver.
The downloadable CBL Isolate – Botanical Product Specifications Sheet provides guaranteed minimum cannabinoid concentration levels and product characteristics you can count on with each order placed.
For your convenience, we have provided a CBL Isolate – Botanical Sell Sheet available for download to keep for yourself or share with others.
Thoughtful Packaging Secures Contents and Promotes Longevity
Our CBL Isolate – Botanical is packaged in either food-grade bags or food-grade HDPE containers. Our stand-up EU & US FDA compliant polyethylene bags hold up to 10 kgs with tear notch and re-closable zipper for easy dispensing and disposal with less environmental waste. The HDPE container preserve freshness and shelf life by reducing light exposure and to help maintain temperature control. The screw-top lid keeps out excess oxygen and other potential contaminants as well as being tamper resistant. Our packaging comes with a label listing the Lot ID number, manufactured date and a QR code to access ISO 17025 accredited third-party CoA reports quickly.
CBL ISOLATE - BOTANICAL | Refined Without Acids or Catalysts Conversions
LEADING THE INDUSTRY IN CBL BOTANICAL REFINEMENT AT SCALE
The production of CBL Isolate – Botanical requires complex refinement and purification processes utilizing advanced chromatographic separation methodologies without chemical conversions. The sophisticated manufacturing process retains the highest concentration of CBL and consistently delivers CBL purity and potency uniformity across batches. Onsite analytical testing throughout manufacturing ensures our CBL Isolate – Botanical meets, and often exceeds, our guaranteed product specifications
ASSURING CBL ISOLATE - BOTANICAL IS OF THE HIGHEST QUALITY
Processed in our FDA Food Registered, cGMP adherent, ISO 9001:2015 certified facility, our CBL Isolate – Botanical is manufactured adhering to both the FDAs dietary supplement (21 CFR Part 111) and to food and beverage (21 CFR Part 117) regulations to ensure quality, potency and purity. Additionally, our in-house lab utilzing advanced equipment, including HPLC units, allows for routine analytical testing throughout manufacturing to evaluate consistency, production controls and optimization of processes.
Why Choose Red Mesa Science & Refining for Your Bulk Cannabinoid Raw Ingredients?
Prioritizing Quality Assurance – Quality is Central to Manufacturing CBL Isolate – Botanical
Quality Assurance is at the heart of our production process. We prioritize quality by operating under stringent guidelines to ensure our customers receive products that abide by regulations and meet or exceed industry standards.
Quality and Regulatory Compliance at the Forefront
- Strict Quality Management System – Under the guidance of ISO 9001:2015 certification and cGMP, our production processes are focused intently on optimal quality and safety.
- Higher Standards – Red Mesa is uniquely held accountable to adhere to both 21 CFR Part 111 (dietary supplements) and 21 CFR Part 117 (food and beverage) standards, furthering our commitment to ensuring our CBL Isolate – Botanical is of the highest quality.
- Internal Testing Protocols – We thoroughly examine, test and analyze the botanically refined CBL Isolate material through to completion. Our team of onsite scientists and chemists perform routine analytical tests throughout production to uphold our promise to guarantee the consistent delivery of products to guaranteed specifications.
- ISO 17025 Accredited Trustworthy and Reliable COAs – Upon completion of manufacturing, final batch-specific testing is administered by an independent ISO 17025 accredited third-party laboratory. The resulting COAs provide added confidence in verifying cannabinoid potency and compliance regarding pesticides, residual solvents, heavy metals, mycotoxins and any other undesirable impurities.