Key Takeaways: The Advantages of Water Soluble CBD, CBG, CBN, Delta 9, CBC and THCV:
機能性飲料、スキンケア、栄養補助食品の需要が高まる中、水溶性CBDは汎用性があり、吸収が早く、安定した結果をもたらすため、ブランドにとって成長機会となる。.
水溶性CBDは水に溶けやすいカンナビジオールの形態で、飲料、スキンケア、その他の水性製品に最適です。ナノエマルジョン技術により、溶解性、安定性、生物学的利用能を高めています。.
- バイオアベイラビリティの向上： ナノサイズの粒子は、血流への吸収をより迅速かつ効率的にする。.
- より早い発症： 肝臓の初回通過代謝を迂回するため、効果がより早く感じられる。.
- 低用量で高い有効性： 吸収率が向上するため、望ましい効果を得るために必要なCBDの量は少なくて済む。.
- 無味無臭： 味や香りを変えることなく、製品にシームレスに溶け込む。.
- 製剤の柔軟性： 飲料、エディブル、スキンケアなどに簡単にブレンドできる。.
- 安定性の向上： ナノエマルジョンは分離を防ぎ、CBDの均一な分布を保証する。.
- 費用対効果： 効果的な結果を得るために必要なCBD原料は少ない。.
- 乳化剤は必要ない： 余分な添加物を使用せず、製品の透明性と滑らかな質感を維持。.
- 10% 濃度 正確な処方の標準用量製品に最適。.
- 20% 濃度 高力価のCBD用途に適しており、材料コストを削減できる。.
レッドメサはcGMPおよびISO認定基準を遵守し、透明性とコンプライアンスのために第三者機関であるISO17025認定のCOAを提供しています。これにより、安全性、純度、規制遵守が保証されます。.
目次
新市場進出のチャンス
As the market for cannabinoid-infused wellness products continues to expand, particularly in the functional beverage, skincare, cosmetics and nutraceutical industries, so too does the demand for high-quality, safe and compliant Water Soluble CBD (cannabidiol), CBG (cannabigerol), CBN (cannabinol), THCV (Tetrahydrocannabivarin), CBC (Cannabichromene) and Delta 9 THC (Delta-9-tetrahydrocannabinol) raw ingredients that blend seamlessly into water-based formulations. While the same methods for creating water-solubility apply to CBD, CBG, CBN, THCV, CBC and Delta 9, we will keep the discussion focused largely on CBD to help simplify it.
水溶性CBDとは？
Traditional CBD isolate and CBD distillate are hydrophobic by nature, meaning they are oil-based and will not dissolve in water. While ideal for oil-based products, such as oil-based tinctures, creams and salves, this type of raw ingredient is not optimal for beverages, serums, skincare, cosmetics or other water-based formulations.
Water-Soluble CBD, on the other hand, is a form of cannabidiol that dissolves quickly and suspends evenly in water or water-based products. Various methods are used to create water-soluble cannabinoids, with nanoemulsion being the most common and effective. However, it bears mentioning that other methods may be desired for specialized applications. The following are the main methods used to manufacture water-soluble cannabinoids and briefly touch on how each works and why it would be preferred over the other.
Which Water-Soluble Technology is Best for Your Water-Based Formulations?
Nanoemulsion
How it works
CBD oil is reduced down to extremely small droplets (typically 20–200 nm) and stabilized with food-grade emulsifiers using high-energy processes, such as high-pressure homogenization or ultrasonication, to ensure the droplets remain suspended in water.
Why manufacturers choose it
- Strong stability in beverages
- Faster onset and improved bioavailability
- Scales well for commercial production
- Accepted across nutraceutical, cosmetic and food & beverage applications
Pros
- Works in clear or cloudy drinks
- Consistent dosing
- Predictable onset
- Versatile delivery
- Broader application compatibility
- High translucency
Cons
- Requires specialized equipment
- Stability depends on emulsifier system quality
Best for
- Functional drinks and shots
- Gummies and edibles
- チンキ剤
- Pharmaceuticals and nutraceuticals
- Skincare and cosmetics
Microemulsion (Thermodynamic Emulsion)
How it works
Uses very high surfactant levels to create a self-assembling, transparent emulsion. Particle sizes are small, but the system relies on chemical balance rather than mechanical force.
Why manufacturers choose it
- Optical clarity
- Less mechanical processing
Pros
- Clear appearance
- Easy lab-scale formulation
Cons
- High surfactant load (taste, regulatory concerns)
- Potential instability upon dilution
Best for
- R&D
- Niche products
- Low-volume pharmaceuticals and nutraceuticals
- Skincare and cosmetics
Inclusion Complexes (Cyclodextrins)
How it works
CBD molecules are encapsulated inside a ring-shaped carrier molecule (usually cyclodextrin), allowing them to disperse in water.
Why manufacturers choose it
- Powder format
- Improved bioavailability and stability
- Useful for dry blends
Pros
- Enables water-dispersible powders
- Long shelf life
- Controlled release potential
- Versatile delivery
Cons
- Lower cannabinoid loading efficiency
- Higher ingredient cost
- Less suitable for beverages than nanoemulsions
Best for
- Powders
- Capsules
- Sachets
- Dry functional blends
Liposomes
How it works
CBD is encapsulated inside phospholipid bilayer spheres (similar to cell membranes), allowing dispersion in water.
Why manufacturers choose it
- Perceived “advanced delivery”
- Improved bioavailability
Pros
- Good absorption potential
- Familiar in nutraceuticals
Cons
- Expensive
- Less stable in beverages
- Sensitive to heat, pH and shear
Best for
- Supplements
- Softgels
- Premium nutraceuticals
- High-end skincare and cosmetics
- Food
Polymer Encapsulation / Spray-Dried Emulsions
How it works
CBD is emulsified and then spray-dried into a powder using carriers like maltodextrin or modified starch.
Why manufacturers choose it
- Powder formulation requirements
- Easy shipping and storage
- Improved stability and solubility
Pros
- Shelf-stable powders
- Easy to dose into dry formulations
- Potential for controlled and targeted release
- Ease of handling
- Increased stability and bioavailability
Cons
- Required high heat could degrade some active compounds
- Material loss may occur with particles adhering to inner walls of drying chamber
Best for
- Drink mix powders
- Bulk ingredient distribution
Why One Water Soluble Method Is Chosen Over Another
| PRIORITY | BEST METHOD |
|---|---|
|
飲料 |
Nanoemulsion |
|
Fast Onset |
Nanoemulsion |
|
Clear Drinks |
Nanoemulsion / Microemulsion |
|
Powder Products |
Cyclodextrin / Spray-dried |
|
Lowest Sensory Impact |
Nanoemulsion / Cyclodextrin / Spray-dried |
|
Scalability |
Nanoemulsion / Cyclodextrin / Spray-dried |
Above all, it is crucial that the water-compatible cannabinoid raw material be stable and retain its original health and wellness benefits while remaining tasteless and translucent in solution.
Given the benefits of nanoemulsions and their well-established use in the pharmaceutical, nutraceutical, food, skincare and cosmetic industries, nanoemulsions are often the preferred method for developing water-based products in the hemp industry.
How Is Nanoemulsion Water Soluble CBD Made?
レッドメサ 水溶性CBD, 水溶性CBG と 水溶性CBN start with 99%+ high-purity isolates manufactured within the 50,000 sq. ft. cGMP, ISO accredited, FDA-registered food facility.
The manufacturing process begins with the highest-quality US-grown hemp crude oil, which undergoes a 6-point quality verification process before continuing on to refining and purification.
- 均質化と溶剤回収： 原油はまず均一性を確保するためにホモジナイズされる。この工程は、精製前に残留溶剤を除去する溶剤回収工程と組み合わされる。.
- 蒸留： その後、オイルは2段階の蒸留工程を経る。この精製方法により、オイルは高純度の蒸留液に精製される。.
- 結晶化： The distillate is further purified through crystallization. This isolates the target cannabinoid, removing other cannabinoids, terpenes and impurities to produce a ≥ 98%-99% pure isolate.
- 後処理の均質化： To ensure consistent quality across production runs, multiple batches of isolate are homogenized. This process ensures uniformity in potency, color and aroma.
- ナノ乳化： The homogenized isolate progresses on to Red Mesa’s advanced nanoemulsion system to reduce cannabinoid molecules into nano CBD, CBG and CBN particles and encapsulate them within a food-grade emulsifier.
Each manufacturing stage, from input hemp material to the finished water-soluble cannabinoid raw ingredient, is highly controlled with testing throughout to maintain process optimization.
Why is Water Solubility Important for Product Formulations?
How Does Water Solubility Enhance Customer Satisfaction?
- バイオアベイラビリティの向上： バイオアベイラビリティとは、CBDのような物質が血流に吸収される速度と程度を指します。水溶性のCBD、CBG、CBN、デルタ9、CBC、THCVは、ナノサイズの粒子のため、より効率的に血流に吸収されます。これらのナノサイズの液滴は表面積が大きく、カンナビノイドが口や胃の粘膜などの粘膜に直接浸透することを可能にします。.
- より早い効果発現： This method of absorption bypasses the liver’s first-pass metabolism, enabling cannabinoids to enter the bloodstream directly with higher retention and a faster onset of effects. This makes it an ideal choice for beverages, tinctures and functional foods like gummies, where quick relief is highly desired.
- Lower Dosage to Achieve Desired Effect: With more of the active compounds reaching the bloodstream, less CBD, CBG, CBN, Delta-9, CBC, or THCV is required to achieve the targeted effects. Furthermore, the homogeneous nature of Red Mesa’s water-soluble products enables precise and consistent dosing throughout each production batch, improving predictability and consistency.
- 無味無臭： In solution, the encapsulation of CBD, CBG, CBN, Delta 9, CBC and THCV acts as a physical barrier, minimizing direct contact with the hemp flavor or aroma that some may find unpleasant. This allows for a cleaner, more neutral flavor profile in the final product without relying heavily on masking agents or added flavoring. Additionally, the smooth texture can make the raw ingredient less oily or gritty, resulting in a smoother mouthfeel and improved palatability.
How Does Water Solubility 製品処方と製品開発の強化
Water-soluble CBD, CBG, CBN, Delta-9, CBC, and THCV offer significant opportunities for market expansion and product diversification. For product formulators and large-scale manufacturers, these water-compatible cannabinoids can expand product breadth to include beverages, water-based nutraceuticals, edibles, and topical products, all of which capitalize on increased bioavailability and more accurate dosing. Formulating with Water Soluble CBD, CBG, CBN or Delta 9 offers:
- 製剤の柔軟性： 水溶性カンナビノイドは素早く溶け、RTD飲料、チンキ剤、グミ、ジェル、スキンケア、化粧品など、さまざまな水性消費者製品に簡単に溶け込む。この汎用性により、即効性のあるリリーフを求めるウェルネス愛好家から、吸収が早く軽量で効果的なスキンケアや化粧品に関心のある消費者まで、幅広い顧客層に対応する製品ラインを拡大することができる。.
- 安定性の向上： Nano-sized cannabinoid particles ensure that CBD, CBG, CBN and D9 dissolve easily and suspend evenly in water-based formulations, helping to prevent phase separation and minimize coalescence risk. This creates a uniform and stable dispersion, ensuring the active ingredients remain evenly distributed over time.
- 乳化剤の添加は不要： Formulations using Water Soluble CBD, CBN, CBG and Delta 9 remain transparent in solution, smooth in texture and shelf-stable, without requiring the addition of gums or surfactants during end-product formulation.
- メーカーにとって費用対効果が高い： 水溶性CBD分離物はより少ない原料で効果的な結果をもたらすため、ブランドは製品の性能を高めながら原料コストを削減することができる。.
一旦製品に混合されると、当社の水溶性カンナビノイドは溶液中で浮遊し、安定性を高める鍵となります。.
予測可能な結果を伴う製品の多様性が顧客満足度を高める
Consumers demand efficacy and consistency from their wellness products, and with CBD, CBG, CBN or Delta 9, it is no different. Thanks to nanoemulsion technology, water-soluble cannabinoids offer greater stability and bioavailability while allowing for the addition of preferred consumption methods to product line ups.
What are the Top Applications for Water Soluble CBD?
- 飲み物： 飲料部門は爆発的な成長を遂げている。 2024年から2031年までの年間平均成長率（CAGR）は24.2%である。. From sports drinks and energy shots to CBD-infused sparkling waters and cocktails, water-soluble CBD, CBG, CBN, Delta 9, CBC and THCV integrate effortlessly into ready-to-drink (RTD) formulations. The neutral flavor and transparency help preserve the intended taste and visual profile, while the uniform dispersion helps mitigate separation.
- エディブルとサプリメント： Gummies, baked goods and dietary supplements benefit greatly from the precise, predictable dosing and enhanced stability offered by water-soluble CBD, CBG, CBN, Delta 9, CBC and THCV.
- スキンケア、化粧品、その他外用剤： 油分を含まない、効果の高い水性ジェル、美容液、クレンジング、保湿剤、スプレーを処方する。水溶性カンナビノイドの生物学的利用能が向上しているため、吸収がよく、化粧品、スキンケア、治療用外用剤に最適です。.
- 高度なデリバリーシステム： 経皮パッチ、経口スプレー、溶解可能な錠剤は、ナノCBDを活用することで、より迅速な全身への送達を実現し、健康志向で結果重視の購入者にアピールしている。.
水溶性カンナビノイドを使用する戦略的利点とは？
大規模製造において、成分の物理的特性と性能は非常に重要であり、生産効率、拡張性、材料コストに直接影響します。 当社の 水溶性CBD, 水溶性CBG, 水溶性CBN と 水溶性デルタ9THC は、10%と20%の両方の濃度で提供され、特定の処方や予算要件に柔軟に対応できるようになっている。.
- 10% 濃度 標準用量製品の理想的なソリューション。単位あたりのカンナビノイド含有量がより低いことが要求される精密な製剤を提供し、大量ロットでの一貫性を確保します。.
- 20% 濃度 高力価の用途向けに設計されている。この高濃度化により、最終製品の力価を高めたり、投入原料を減らして原料コストを削減することができる。.
How to Build Trust in Manufacturing
明確なラベリングとISO-17025第三者認証の最終分析証明書（COA）。.
水溶性CBDは、cGMPおよびISO認定ガイダンスの下で製造され、規制遵守と透明性を保証します。フルパネル ISO 17025認定サードパーティCOA文書 confirming potency, brands can instill consumer trust and confidence in market products, knowing they meet, if not exceed, strict industry standards.
レッドメサ・サイエンス＆リファイニングの詳細
レッドメサ社はどのようにして水溶性CBDの品質を保証しているのですか？
Red Mesa Science & Refining is the ideal partner for product formulators seeking bulk water-soluble CBD, CBG, CBN, Delta 9 and other cannabinoid raw materials. Red Mesa’s commitment to オペレーショナル・エクセレンス, quality, and innovation is evident in its adherence to cGMP, ISO 9001:2015 certification, conformance with 21 CFR Parts 111 & 117, と FDA food facility registration, all of which exceed industry standards. This ensures that Red Mesa products consistently meet, if not exceed, the highest quality benchmarks, offering formulators peace of mind regarding safety, purity and regulatory compliance.
なぜレッドメサは世界中で選ばれているのか？
Red Mesa’s significant investment in advanced manufacturing capabilities and processes is rare in the industry. Additionally, Red Mesa’s in-house labs for process optimization and traceable production processes ensure reliability and transparency for added confidence. This, combined with Red Mesa’s customer-centric approach, including collaborative support and timely deliveries, fosters long-term partnerships and drives Red Mesa’s success.
レッドメサは、単離物から蒸留物、水溶液に至るまで、幅広い製品群を取り揃えており、大規模な産業用途から小規模な研究開発プロジェクトまで対応できる柔軟な注文数量で、多様な製剤ニーズにお応えしています。品質、革新性、信頼できるサプライチェーンを優先する製剤メーカーにとって、Red Mesa Science & Refiningはヘンプ業界の明確なリーダーです。.
Strategically, It’s Time to Take the Next Step to Remain Competitive
Integrating water-soluble CBD into your product portfolio should no longer just be an option, but rather imperative to remaining competitive. Partnering with a reliable, well-established water-soluble manufacturer is essential to your brand integrity and to meet your quality and scalability needs. As a proven global hemp-derived manufacturer of cannabinoid raw materials, Red Mesa is well-positioned to help grow your brand.
